Ian A Shiels Selected Research

Atherosclerotic Plaque (Atheroma)

7/2011

Complement C5a inhibition reduces atherosclerosis in ApoE-/- mice.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Ian A Shiels Research Topics

Disease

7	Reperfusion Injury 12/2006 - 04/2002
5	Wounds and Injuries (Trauma) 12/2006 - 04/2002
5	Neutropenia 08/2006 - 04/2002
5	Edema (Dropsy) 08/2005 - 04/2002
3	Inflammation (Inflammations) 01/2016 - 01/2006
3	Necrosis 03/2011 - 11/2002
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 08/2005 - 11/2003
3	Colitis 08/2005 - 11/2003
3	Ischemia 01/2004 - 04/2002
2	Neoplasms (Cancer) 01/2021 - 01/2011
2	Arthritis (Polyarthritis) 03/2011 - 09/2002
2	Body Weight (Weight, Body) 08/2005 - 05/2005
2	Hypotension (Low Blood Pressure) 09/2003 - 11/2002
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Carcinoma (Carcinomatosis) 01/2021
1	Tachycardia (Tachyarrhythmias) 02/2014
1	Atherosclerotic Plaque (Atheroma) 07/2011
1	Atherosclerosis 07/2011
1	Rheumatoid Arthritis 03/2011
1	Dog Diseases (Disease, Canine) 03/2010
1	Shock 08/2006
1	Burns 08/2006
1	Sepsis (Septicemia) 08/2006
1	Lung Injury 08/2006
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 08/2006
1	Hemorrhagic Shock 08/2006
1	Huntington Disease (Huntington's Disease) 07/2006
1	Proteinuria 01/2004
1	Weight Gain 11/2003
1	Hemorrhage 01/2003
1	Hematuria 01/2003
1	Bradycardia 11/2002

Drug/Important Bio-Agent (IBA)

9	Anaphylatoxin C5a ReceptorIBA 01/2016 - 04/2002
8	Complement System Proteins (Complement)IBA 01/2021 - 04/2002
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2010 - 04/2002
5	AcPhe(ornithine- Pro- cyclohexylamine- Trp- Arg)IBA 01/2006 - 04/2002
4	Peroxidase (Myeloperoxidase)IBA 05/2005 - 01/2003
3	Secretory Phospholipases A2IBA 03/2011 - 09/2003
3	Cyclic PeptidesIBA 01/2006 - 04/2002
3	Pharmaceutical PreparationsIBA 08/2005 - 11/2003
3	Sulfonic AcidsIBA 08/2005 - 11/2003
3	Aspartate Aminotransferases (Aspartate Transaminase)IBA 09/2003 - 04/2002
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2004
2	Messenger RNA (mRNA)IBA 01/2021 - 01/2011
2	Atenolol (Tenormin)FDA LinkGeneric 01/2016 - 02/2014
2	EnzymesIBA 03/2011 - 05/2005
2	Infliximab (Remicade)FDA Link 03/2011 - 11/2003
2	Prednisolone (Predate)FDA LinkGeneric 03/2011 - 11/2003
2	AntigensIBA 03/2011 - 09/2002
2	Group II Phospholipases A2IBA 03/2011 - 05/2005
2	hydrocinnamate- cyclo(ornithyl- prolyl- cyclohexylalanyl- tryptophyl- arginyl)IBA 07/2006 - 08/2005
2	Factor VaIBA 08/2005 - 04/2002
2	CreatinineIBA 01/2004 - 01/2003
1	Tyr(65)-Phe(67)-Pro(69,71)-Ala(73)- (65-74) complement C5aIBA 01/2021
1	Peptides (Polypeptides)IBA 01/2021
1	Complement Receptors (Complement Receptor)IBA 01/2021
1	Apolipoproteins E (ApoE)IBA 07/2011
1	Complement C5a (Complement 5a)IBA 07/2011
1	Leflunomide (Arava)FDA LinkGeneric 03/2011
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 03/2011
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2011
1	Etanercept (Enbrel)FDA Link 03/2010
1	carprofen FDA Link 03/2010
1	cobra venom factorIBA 08/2006
1	3-nitropropionic acidIBA 07/2006
1	Dihydrotachysterol (AT 10)IBA 08/2005
1	sym-trinitrobenzeneIBA 08/2005
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 05/2005
1	Phospholipases (Phospholipase)IBA 05/2005
1	AcidsIBA 05/2005
1	cyclohexylalanineIBA 11/2003
1	Celecoxib (Celebrex)FDA Link 09/2003
1	zafirlukast (Accolate)FDA LinkGeneric 09/2003
1	Leukotriene C4IBA 09/2003
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 09/2003
1	Ethanol (Ethyl Alcohol)IBA 01/2003
1	pirfenidoneIBA 11/2002
1	Ibuprofen (Motrin)FDA LinkGeneric 09/2002
1	methylated bovine serum albumin (MBSA)IBA 09/2002
1	HaptoglobinsIBA 04/2002
1	phenylalanyl(ornithinyl- prolyl- cyclohexylalanyl- tryptophyl- arginyl)IBA 04/2002

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 12/2006 - 05/2004
1	Therapeutics 03/2011
1	Intravenous Infusions 08/2006
1	Topical Administration 01/2006
1	Oral Administration 01/2006
1	Controlled Hypotension 01/2006
1	Intra-Articular Injections 09/2002